Fig. 4.
Model of tubulin–VDAC interaction. One tubulin CTT partially blocks channel conductance by entering VDAC pore. This process is voltage-dependent and could be described by the 1st-order reaction of one-to-one binding of tubulin to VDAC. Some additional interaction between tubulin globular body and VDAC may be involved. The model of a tubulin dimer was redrawn from ref. 17.