TABLE 1.
Data collection and refinement statistics
| WDR5-MLL | |
|---|---|
| Data Collection | |
|
Space group
|
C2221 |
| Unit cell dimensions | |
| a, b, c (Å) | 78.16, 97.71, 79.82 |
| α = β = γ (°) | 90 |
| Resolution (Å) | 50-1.37 (1.42-1.37)a |
| Rsymb | 0.059 (0.25) |
| I/σ(I) | 36.1 (3.1) |
| Completeness (%) | 99.0 (99.3) |
|
Redundancy
|
7.4 (3.9)
|
| Refinement | |
| Resolution (Å) | 50-1.37 |
| No. unique reflections | 64701 |
| Rwork/Rfreec | 0.1903/0.1998 |
| No. atoms | 2678 |
| Protein | 2403 |
|
Water/ion
|
275
|
| B-factors | |
| Protein | 10.754 |
|
Water/ion
|
23.169
|
| R.m.s. deviations | |
| Bond length (Å) | 0.004589 |
| Bond angles (°) | 1.898 |
| Ramachandran (%) | 89.4 (10.6)d |
a
Values in parenthesis are for the highest-resolution shell.
b
∑(Ihkl - <Ihkl>)/∑<Ihkl>, where <Ihkl> is the mean intensity of all reflections equivalent to reflection hkl by symmetry.
c
∑||Fo| - |Fc||/∑Fo| where 5% of randomly selected date was used for Rfree.
d
Value in parenthesis is for additional allowed regions.