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. Author manuscript; available in PMC: 2008 Dec 5.
Published in final edited form as: Org Lett. 2005 Jun 23;7(13):2571–2573. doi: 10.1021/ol050630b

Table 4.

Preparation of Different β2-Amino Acids

graphic file with name nihms63773t4.jpg

entry R yield, (SM)%a ee, %b
1 Phenyl 6a 91 88
2 4-Chlorophenyl 6h 71 (10) 84
3 4-Methylphenyl 6i 16 (62) 63
4 4-Methoxyphenyl 6j 84 86
5 3,5-Bistrifluoromethylphenyl 6k 70 (23) 90
6 2-Naphthyl 6l 95 91
a

Isolated yields. Yields in parenthesis are for recovered starting materials.

b

Chiral HPLC analysis.