Table 2.
Mean ± s.d. of CBF, CBV, and MTT values averaged over the normal-appearing white matter and over the deep gray matter nuclei of healthy controls, RR-MS, and PP-MS patients
| Healthy controls | RR-MS patients | PP-MS patients | ||||
|---|---|---|---|---|---|---|
| Deep GM | WM | Deep GM | NAWM | Deep GM | NAWM | |
| CBF (ml/100 g/min) | 68.2±7.1 | 42.4±5.9 | 62.9±7.8 | 32.7±4.9 | 57.2±8.4 | 27.3±4.5 |
| CBV (ml/100 g) | 4.8±0.6 | 3.1±0.7 | 4.5±0.7 | 2.4±0.5 | 3.9±1.0 | 1.9±0.6 |
| MTT (seconds) | 4.3±0.6 | 4.4±0.7 | 4.3±0.7 | 4.3±0.6 | 4.0±0.9 | 4.2±1.0 |
CBF, cerebral brain flow; CBV, cerebral brain volume; GM, gray matter; MTT, mean transit time; NAWM, normal-appearing white matter; PP-MS, primary-progressive multiple sclerosis; RR-MS, relapsing-remitting multiple sclerosis; s.d., standard deviation; WM, white matter.
Values are given as means ± s.d. and adjusted for age, gender, and disease duration.