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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Cancer Res. 2008 Dec 1;68(23):9928–9934. doi: 10.1158/0008-5472.CAN-08-2051

Fig. 3. Cervical cancers are associated with ASM in mice.

Fig. 3

(A) Estrogen-treated K14E7/ERα−/− mice lack ASM. H&E-stained reproductive tracts of mice described in Table 1 were examined for the presence of ASM. Representatives of each genotype are shown and arrowheads indicate ASM. (B) E6 and E7 contribute to ASM independently. H&E-stained archival reproductive tracts of indicated mice that are treated with 17β-estradiol (+E2) for 6 months (top panel) or untreated (-E2) (middle panel) were analyzed for the presence of ASM (20). Reproductive tracts of ovariectomized and untreated K14E7 mice were also examined (bottom panel). Arrowheads indicate ASM and representatives of each group of mice are shown. Number of ASM-positive mice over total number of mice analyzed is shown at right lower corner of each image.