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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Drug Metab Dispos. 2008 Sep 17;36(12):2452–2459. doi: 10.1124/dmd.108.023960

Figure 2.

Figure 2

Construction of F344 Nat2 congenic lines. The percentage of F344 genome (open circles) and WKY genome (solid squares) is illustrated for the F1 and each congenic (N) generation. Heterozyous Nat2 acetylator males and females from the N10 generation were bred to produce homozygous rapid and homozygous slow Nat2 acetylator F344 rats.