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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: J Immunol. 2008 Sep 15;181(6):3947–3954. doi: 10.4049/jimmunol.181.6.3947

Figure 2. FRCs connect the MZ to the PALS at the MZBC.

Figure 2

Spleen cryostat sections from HuCD2 GFP (blue) mice were stained for ERTR-7 (green = FRC-derived matrix protein), MOMA-1 (red, panels A and C) or Desmin (panel B) and imaged using confocal microscopy. In panel C, the insert shows a higher magnification of 2 MZBCs. Arrowheads point to the location of MZBCs while “B” indicates the presence of B cell follicles. This picture is representative of 3 different experiments. See also Movie S1.