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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Hepatology. 2008 Nov;48(5):1497–1505. doi: 10.1002/hep.22515

Figure 3. Overexpression of constitutive active Rac1 induces phagocytosis of apoptotic bodies by HSC.

Figure 3

LX-2 cells transfected with Rac1 Q61L, engulfed more apoptotic bodies (1.97-fold, +/-0.17), compared to mock-transfected cells exposed to AB. Transfection of the dominant negative mutant (T17N) resulted in decrease of phagocytosis compared to the Rac1Q61L-transfected cells however, still above the control level (control, only pcDNA3.1-transfected cells). Mean ±SE, N=4, *p<0.01.