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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Calcif Tissue Int. 2008 Sep 24;83(4):251–259. doi: 10.1007/s00223-008-9170-1

Table 2.

Acid-Suppressive Medication Use and Cross-sectional Total Hip Bone Mineral Density

SOF Women (n=5339) MrOS Men (n=5755)
Age Adjusteda Multivariate Adjustedb Age Adjusteda Multivariate Adjustedb


PPI user 0.731 (p=0.63) 0.729 (p=0.37) 0.946 (p=0.06) 0.946 (p=0.05)
H2RA user 0.755 (p<0.01) 0.745 (p=0.13) 0.952 (p=0.35) 0.944 (p=0.06)
PPI or H2RA user 0.748 (p=0.02) 0.741 (p=0.37) 0.947 (p=0.03) 0.945 (p<0.01)
Non-user 0.736 (referent) 0.736 (referent) 0.959 (referent) 0.958 (referent)
a

Adjusted for age and clinic.

b

Adjusted for age, clinic, race, BMI, alcohol use, exercise, oral or inhaled corticosteroid use, NSAID use, calcium supplement use, osteoporosis medication use, and self reported health. SOF results are adjusted for caffeine intake and estrogen use. MrOS results are adjusted for smoking and history of stomach surgery.