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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Endocrinol Metab Clin North Am. 2008 Sep;37(3):635–ix. doi: 10.1016/j.ecl.2008.06.007

Figure 1. Relationship between obesity, insulin resistance, inflammation and atherosclerotic vascular disease.

Figure 1

Obesity causes insulin resistance and a state of low grade inflammation. Both contribute to the development of several disorders, including T2DM, hypertension, dyslipidemia and disorders of coagulation and fibrinolysis which are independent risk factors for the development of atherosclerotic vascular disease. T2DM: Type 2 diabetes mellitus, ASVD: atherosclerotic vascular disease.