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. 2008 Dec 16;3(12):e3948. doi: 10.1371/journal.pone.0003948

Table 1. The effect of vaccination with purified gametocyte antigens of Eimeria maxima on mortality and egg production by breeding hens.

Country Number of hens Mortality (%) Eggs laid per hen
Argentina (Cobb Breed)
Purified gametocyte antigen 4,646 9.08% 152
Control 4,669 17.41% 149
Brasil (Cobb Breed)
Purified gametocyte antigen Farm 1 19,854 15.58% 177
Control Farm 1 19,455 17.82% 177
Purified gametocyte antigen Farm 2 20,100 11.21% 176
Control Farm 2 20,218 14.96% 170
Purified gametocyte antigen Farm 3 18,747 4.09% 192
Control Farm 3 18,734 4.14% 188
Purified gametocyte antigen Farm 4 20,284 9.93% 180
Control 4 19,194 13.14% 178
India (Ross Breed)
Purified gametocyte antigen 3,500 7.9% 182
Control 3,500 10.4% 175

Breeding hens were injected intramuscularly with 50 µg of purified gametocyte antigens emulsified in 0.5 ml of water-in-oil adjuvant at 15 and 20 weeks of age. Mortality rates and egg production of the flocks of hens were monitored until the end of their productive lives (around 60–65 weeks of age). Neither mortality or egg production were affected by vaccination (one-way ANOVA).