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. Author manuscript; available in PMC: 2008 Dec 8.
Published in final edited form as: Biochemistry. 2007 Jan 16;46(2):331–340. doi: 10.1021/bi0621314

Figure 4.

Figure 4

Intermolecular NOEs observed in the 40 kDa complex between EIN and HPR (28). The strips are from 3D heteronuclear edited/filtered NOESY spectra of two differently labeled complex samples in 2H2O solutions. (A) 13C/15N-labeled EIN bound to unlabeled HPR. (B) 13C/15N-labeled HPR bound to unlabeled EIN. Thus, in (A) the interproton NOEs are observed between the 12C-bound protons of HPR and the 13C-bound protons in EIN, whereas in (B), NOEs are observed between 12C-bound protons of EIN and 13C bound protons of HPR. Reproduced from (28) with permission from Nature Publishing.