. Author manuscript; available in PMC: 2009 Sep 1.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2008 Sep 1;72(1):153–160. doi: 10.1016/j.ijrobp.2008.04.072

Table 2.

Genes from Table 1 with links to apoptosis or cancer progression

Gene	Activity
PDLIM5	LIM domains bind to ID2, PDZ domain binds actin (39)
ID2	Blocks proliferation and increases proliferation (40); affects the balance of cell growth and death (41)
DAPK1	Positive mediator of apoptosis (42)
ATRX	In complex with death-domain protein DAXX (43)
SEMA3C	Influences cell migration and may contribute to tumorigenesis and tumor progression (44, 45)
GNAI1	Mutations cause this gene to become an oncogene (46)