Fig.5.
DETA-NONOate co-cultured with the conditioned medium from BMSCs enhances angiogenesis and capillary tube formation which are mediated by increases of the Ang1/Tie2 axis. (A-F) Data of MBEC capillary tube formation in non-treatment control (A), Ang1 200 ng/ml (B), conditioned medium from BMSCs (C), DETA-NONOate 0.4 μM (D), conditioned medium from BMSCs + DETA-NONOate 0.4 μM (E), conditioned medium from BMSCs + DETA-NONOate 0.4 μM + anti-Ang1 antibody 1 μg/ml (F) after 6 hours of culture. (G) Quantitative data of capillary tube formation. Scale bar=100 μm, n=6/group.