Plasma glucose and glucose kinetics. a Plasma glucose prior to (−30 and 0 min) and during (15–60 min) the intraportal infusions in the CON, HYPER, Tun and Thap groups of anaesthetised rats. The vertical dashed lines denote the start of the infusions. b The change in plasma glucose concentration between 0 and 60 min. c Ra and Rd for glucose prior to (Pre) and following (Post) the intraportal infusions in the CON (open bars), HYPER (right hatched bars), Tun (left hatched bars) and Thap (double hatched bars) groups. Pre was calculated from two samples taken at −10 and 0 min. Post was calculated from two samples taken at 45 and 60 min. d The change in the glucose Ra and Rd between 0 and 60 min. Data are reported as the mean±SD for n =5–10 per group. *p<0.05 vs CON, †p<0.05 vs HYPER