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. Author manuscript; available in PMC: 2009 Nov 15.

Published in final edited form as: J Immunol. 2008 Nov 15;181(10):7350–7355. doi: 10.4049/jimmunol.181.10.7350

T1D Teff are resistant to nTreg. T1D Teff were co-incubated with nTreg directly isolated from the peripheral blood, %inhibition at a Treg:Teff ratio of 1:1 is shown for, nTreg with control Teff (●) (n=1) and nTreg with T1D Teff (△) (n=4) at a Treg:Teff ratio of 1:1, nTreg with control Teff (■) (n=4) and nTreg with T1D Teff (▽) (n=6) at a ratio of 1:4. For comparison the level of suppression at 1:4 seen with control aTreg co-incubated with the same T1D Teff cells shown in the nTreg assays is shown ( ).

Inline graphic — T1D Teff are resistant to nTreg. T1D Teff were co-incubated with nTreg directly isolated from the peripheral blood, %inhibition at a Treg:Teff ratio of 1:1 is shown for, nTreg with control Teff (●) (n=1) and nTreg with T1D Teff (△) (n=4) at a Treg:Teff ratio of 1:1, nTreg with control Teff (■) (n=4) and nTreg with T1D Teff (▽) (n=6) at a ratio of 1:4. For comparison the level of suppression at 1:4 seen with control aTreg co-incubated with the same T1D Teff cells shown in the nTreg assays is shown ( ).