Skip to main content
. Author manuscript; available in PMC: 2009 Nov 4.
Published in final edited form as: Cancer Cell. 2008 Nov 4;14(5):382–393. doi: 10.1016/j.ccr.2008.10.005

Fig. 6.

Fig. 6

Blocking of VEGFR2 reduces angiogenesis in vitro (A) HBMVECs were stimulated using U87-conditioned medium and cultured on Matrigel-coated plates in the presence or absence of VEGFR2 blocking antibody, size bar 300 μm. (B) After 24 hr VEGFR2 blocking significantly reduced tubule branching and tubule length. (C) HBMVECs cultured in a monolayer, scratched, and incubated in the presence or absence of VEGFR2 blocking antibody for 24 hr. VEGFR2 blocking resulted in a significant decrease in HBMVEC migration [size bar 300 μm], as quantified in (D). Error bars indicate S.D., ***p < 0.001, t test.