Table 1.
Experimental day |
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5 | 8 | 11 | 15 | 19 | 26 | 29 | 33 | 36 | 40 | 43 | 47 | 54 | 61 | 68 | |
Absolute weight, mg | |||||||||||||||
Mouse 1 | 14 | 63 | 63 | 63 | 63 | 63 | 63 | 63 | 63 | 75 | 75 | 148 | 211 | 307 | 325 |
Mouse 2 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 63 | 63 |
Mouse 3 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 63 | 63 | 63 | 81 | 144 | 253 | 425 |
Mouse 4 | 14 | 14 | 14 | 14 | 14 | 63 | 63 | 63 | 108 | 158 | 196 | 343 | 666 | 1276 | 1744 |
Mouse 5 | 14 | 63 | 63 | 63 | 63 | 63 | 81 | 106 | 144 | 343 | 496 | 817 | 1310 | 2588 | 3752 |
Mouse 6 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 14 | 63 | 63 | 81 | 208 | 425 | 600 |
Median tumor weight | 14 | 14 | 14 | 14 | 14 | 38 | 39 | 39 | 63 | 69 | 69 | 115 | 210 | 366 | 513 |
Average tumor weight | 14 | 30 | 30 | 30 | 30 | 38 | 42 | 46 | 68 | 119 | 151 | 247 | 425 | 819 | 1151 |
SD of average | 0 | 25 | 25 | 25 | 25 | 27 | 31 | 38 | 51 | 119 | 180 | 301 | 486 | 964 | 1401 |
SD of median | 0 | 31 | 31 | 31 | 31 | 27 | 31 | 39 | 52 | 131 | 201 | 334 | 541 | 1084 | 1566 |
t test vs day 68 values | .07 | .08 | .08 | .08 | .08 | .08 | .08 | .08 | .09 | .10 | .11 | .15 | .26 | .64 | NA |
Relative weight† | |||||||||||||||
Mouse 1 | 1.0 | 4.5 | 4.5 | 4.5 | 4.5 | 4.5 | 4.5 | 4.5 | 4.5 | 5.4 | 5.4 | 10.6 | 15.1 | 21.9 | 23.2 |
Mouse 2 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 4.5 | 4.5 |
Mouse 3 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 4.5 | 4.5 | 4.5 | 5.8 | 10.3 | 18.1 | 30.4 |
Mouse 4 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 4.5 | 4.5 | 4.5 | 7.7 | 11.3 | 14.0 | 24.5 | 47.5 | 91.1 | 124.6 |
Mouse 5 | 1.0 | 4.5 | 4.5 | 4.5 | 4.5 | 4.5 | 5.8 | 7.6 | 10.3 | 24.5 | 35.5 | 58.3 | 93.6 | 184.8 | 268.0 |
Mouse 6 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 4.5 | 4.5 | 5.8 | 14.9 | 30.4 | 42.9 |
Average | 1.0 | 2.2 | 2.2 | 2.2 | 2.2 | 2.7 | 3.0 | 3.3 | 4.8 | 8.5 | 10.8 | 17.7 | 30.4 | 58.5 | 82.2 |
SD | 0.0 | 1.8 | 1.8 | 1.8 | 1.8 | 1.9 | 2.2 | 2.7 | 3.7 | 8.5 | 12.8 | 21.5 | 34.7 | 68.8 | 100.1 |
Tumor weights were calculated as tumor weight (mg) = (tumor length × tumor width2)/2. Tumors that are shown as weighing 14 mg were estimated as being 3 × 3 mm because they were palpable but too small to be accurately measured with calipers. NA = not applicable.
Relative tumor weight = (day T weight/day 5 weight), where day T is each time point beyond the day-5 starting mass.