Table 1. EC₅₀ values of TRPM2 (in μM) and single-channel conductance (in pS) in different cell types.

	HEK293-TRPM2	Neutrophil	Jurkat T	U937	RIN5mf
In [μM]
ADPR (BAPTA)	200f 90a (Cs+)	No activationg (1 mM)	n.d.	130a (at 0.1 μM [Ca2+]i, Cs+)	240 (Cs+) (Fleig, unpublished)
ADPR unbuffered	10c,f	1e,g (K+, Cs+)	7d 15d (Cs+)	40a (Cs+)	20 (Cs+) (Fleig, unpublished)
cADPR unbuffered	700c 120d (Cs+)	44g	60d (K+, Cs+)	n.d.	n.d.
NAADP unbuffered	730d	95g	Activatesd (1 mM)	n.d.	n.d.
ADPR [var.] + 10 cADPR unbuffered	0.09c	n.d.	Facilitates	n.d.	n.d.
0.1 ADPR + cADPR [var.] unbuffered	n.d.	3g	n.d.	n.d.	n.d.
0.1 ADPR + NAADP [var.] unbuffered	n.d.	1g	n.d.	n.d.	n.d.
[Ca2+]i	0.05f 0.34b (Cs+)	0.3g	n.d.	n.d.	n.d.
Single Channel (in pS)	60a (Na+)	56i (Cs+) 43/63g (Cs+)	67d (Cs+)	n.d.	(CRI-G1 cells) 68h (Na+)

Values were assessed in K⁺-based intracellular conditions unless indicated otherwise (n.d. = not determined; unbuffered = absence of calcium chelators; [var.] = variable concentrations). Literature:

^aPerraud et al., 2001;

^bMcHugh et al, 2003;

^cKolisek et al, 2005;

^dBeck et al., 2006;

^eHeiner et al, 2006;

^fStarkus et al, 2007;

^gLange et al, current manuscript;

^hHerson & Ashford, 1997;

ⁱHeiner et al, 2003.