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Effect of chondroitin-4-sulphate (C4S) treatment on hepatic metalloprotease (MMP)-9 mRNA expression (a) and MMP-9 protein production (b, c) in livers of mice injected with carbon tetrachloride (CCl4). Values are the mean±s.d.mean of seven experiments and are expressed as n-fold increase with respect to the control (a) and as both densitometric analysis (c) and western blot analysis (b) for the MMP-9 protein levels. °P<0.001 vs control; *P<0.05, **P<0.005 and ****P<0.001 vs CCl4.
