Table 1.

Effect of C4S treatment on serum AST and ALT levels in mice after CCl₄ injection

Experimental group	AST	ALT
Control (untreated)	34.5±4.2	20.8±3.2
C4S alone (120 mg kg−1)	31.2±4.3	23.4±3.4
CCl4	187.7±21.4†	158.2±18.1†
CCl4+C4S (30 mg kg−1)	140.2±17.4*	112.1±15.5*
CCl4+C4S (60 mg kg−1)	110.4±16.1*	88.3±13.6*
CCl4+C4S (120 mg kg−1)	87.6±13.2*	61.7±12.4*

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; CCl₄, carbon tetrachloride; C4S, chondroitin-4-sulphate.

Values are the mean±s.d.mean of seven experiments and are expressed as U L⁻¹.

^†P<0.001 vs control; ^*P<0.001 vs CCl₄.