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. 2008 Sep 1;155(7):1104–1116. doi: 10.1038/bjp.2008.340

Figure 3.

Figure 3

Effects of i.p. administration of MDA7 on the hind paw withdrawal latency in response to noxious heat in naive rats (n=10 per group). (a) The time course of percent maximal possible effect (%MPE) and (b) the area under the curve (AUC) of 1.0, 3.0 and 10 mg kg−1 of MDA7 and the vehicle. *P<0.05 compared with other groups. +P<0.05 compared with 3.0 or 10 mg kg−1 of MDA7 and the vehicle (ANOVA followed by Tukey–Kramer test for multiple group comparison). #P<0.05 compared with 1.0 and 3.0 mg kg−1 of MDA7 (ANOVA followed by Tukey–Kramer test for multiple group comparison). Each point represents the mean±s.e.mean.