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. 2008 Sep 1;155(7):1104–1116. doi: 10.1038/bjp.2008.340

Figure 7.

Figure 7

Effects of MDA7 administered by i.p. injection on tactile allodynia in a paclitaxel-induced neuropathic pain model in rats (n=8 per group). MDA7 dose-dependently attenuated tactile allodynia in this model, as shown by an increase in the percentage maximal possible effect (%MPE) withdrawal threshold area under the curve (AUC). *P⩽0.05 compared with 10 and 15 mg kg−1 of MDA7 (ANOVA followed by Tukey–Kramer test for multiple group comparison). +P⩽0.05, P<0.05 compared with 15 mg kg−1 of MDA7 (ANOVA followed by Tukey–Kramer test for multiple group comparison).