Ishak Score |
|
0 |
No fibrosis |
1 |
Fibrous expansion of some portal areas, with or without short septae |
2 |
Fibrous expansion of most portal areas, with or without short septae |
3 |
Fibrous expansion of most portal areas with occasional portal to portal (P-P) and/or portal to central (P-C) bridging |
4 |
Fibrous expansion of portal areas with marked bridging (P-P as well as P-C) |
5 |
Marked bridging (P-P as well as P-C) with occasional nodules (incomplete cirrhosis) |
6 |
Cirrhosis (probable or definite) |
PBC Stage |
|
1 |
No fibrosis. (There had to be some portal inflammation on the initial biopsy in order to be enrolled). |
2 |
Non- bridging fibrosis. (Portal tracts expanded beyond the limiting plate with any degree of fibrosis less than stage 3.) |
3 |
Bridging fibrosis (Two or more portal-portal bridges) |
4 |
Cirrhosis (at least one regenerative nodule surrounded by fibrosis) |