Table 3.
Test | Subgroup | Subgroup Value | Clinical Event* | |
---|---|---|---|---|
Yes | No | |||
ELF† | Low | -1.32 to -0.08 | 4 (8%) | 49 (92%) |
Intermediate | -0.06 to 0.669 | 13 (24%) | 41 (76%) | |
High | 0.67 to 3.23 | 25 (46%) | 29 (54%) | |
Ishak Score | Low | 0 - 1 | 1 (4%) | 25 (96%) |
Intermediate | 2 - 3 | 25 (25%) | 74 (75%) | |
High | 4 - 6 | 16 (46%) | 19 (54%) | |
PBC Stage | Low | <2.0 | 12 (17%) | 57 (83%) |
Intermediate | 2.0 -2.9 | 12 (20%) | 47 (80%) | |
High | 3-4 | 18 (55%) | 15 (45%) | |
Bilirubin | Low | ≤ 1.0 | 32 (22%) | 114 (78%) |
Intermediate | 1.1 - 2.0 | 8 (62%) | 5 (38%) | |
High | > 2.0 | 2 (100%) | 0 (0%) | |
MELD | Low | ≤ 6.0 | 24 (20%) | 95 (80%) |
Intermediate | 7-10 | 17 (41%) | 24 (59%) | |
High | ≥ 11 | 1 (100%) | 0 | |
Mayo Risk | Low | < 3.5 | 8 (14%) | 48 (86%) |
Intermediate | 3.5-3.9 | 9 (21%) | 34 (79%) | |
High | ≥ 4.0 | 25 (40%) | 37 (60%) |
ELF is categorized by tertiles
p< 0.004 for all prognostic tests, event group versus no event group, comparison by Cochran-Armitage Trend test