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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: J Immunol. 2008 Sep 15;181(6):4124–4130. doi: 10.4049/jimmunol.181.6.4124

Figure 4. Omenn Syndrome mutants display weak, hypomorphic activity with all coding flank sequences.

Figure 4

Plasmids containing RAG1 R621C, R621H, E719K, C897X, or Y909C and wild-type RAG2 plus each of sixteen coding joint substrates or sixteen signal joint substrates were transfected into CHO cells and analyzed by FACS. Percentage of GFP-positive cells is shown. Error bars represent standard error of the mean of ≥3 experiments.