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. Author manuscript; available in PMC: 2009 May 27.
Published in final edited form as: Nature. 2008 Nov 2;456(7221):464–469. doi: 10.1038/nature07488

Figure 2. Nova-RNA interaction maps associated with the Nova-dependent splicing regulation.

Figure 2

a, CLIP tags around all known Nova-regulated cassette exons; one color per transcript. Tags were mapped onto a composite transcript containing an alternative (dark blue/red box) and flanking constitutive (light blue box) exons. Tags are from transcripts showing Nova-dependent exon inclusion (top panel) or exclusion (bottom panel); experimental validation is shown (insets). b, Normalized complexity map (see methods) of Nova-RNA interactions recapitulate predicted maps18 (insets) for Nova-dependent exon inclusion (red) or exclusion (blue).