Figure 1.
Reaction schemes for the ornithine hydroxylase (PvdA) from P. aeruginosa (a), the lysine hydroxylase (IucD) from E. coli (b), p-hydroxybenzoate hydroxylase (PHBH) from P. fluorescens (c), and flavin-containing monooxygenase (FMO) from hog liver microsomes (d). The substrate for PHBH (p-hydroxybenzoate) and FMO (nucleophilic and some electrophilic compounds) is labeled as Sub and the flavin states are labeled as oxidized (Flox), reduced (Flred), hydroperoxyflavin intermediate (FlHOOH), and hydroxyflavin intermediate (FlHOH).
