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. Author manuscript; available in PMC: 2009 Jul 8.
Published in final edited form as: Cancer Cell. 2008 Jul 8;14(1):68–78. doi: 10.1016/j.ccr.2008.05.017

Figure 5. Disruption of SCFFbx4/αB-crystallin activity leads to nuclear accumulation of cyclin D1.

Figure 5

A. Immunofluorescence was performed on the indicated cell lines using the 13G11 cyclin D1 monoclonal antibody and counterstained with DAPI (bar, 25 µM). B. Quantification of A. C. Protein extracts from stable NIH3T3 cell lines expressing shFbx4 or shαB-crystallin were analyzed by Western Blot using Cdt1 and cyclin D1 antibodies.