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. Author manuscript; available in PMC: 2008 Dec 8.
Published in final edited form as: J Proteome Res. 2007 Jan;6(1):348–357. doi: 10.1021/pr060488o

Table 1.

Comparison of gene expression changes at the mRNA and protein levels in 1-day-old transgenic Drosophila vs. age-matched controls.

Gene name or IDa,b Flybase IDb PHc (control) PHc (transgenic) PH ratiod PH P-valuee mRNAf
CG8732a FBgn0010609 2 0 0 0.1835 ↓
CG15515a FBgn0039719 2 0 0 0.1835 ↑
Puncha FBgn0003162 23 10 0.43* 0.0198* ↓
Hennaa FBgn0001208 12 8 0.67 0.2065 ↓
purplea FBgn0003141 6 4 0.67 0.5666 ↑
adenosine5a FBgn0020513 14 11 0.79 0.3785 ↓
CG13044a FBgn0036599 5 4 0.8 0.5185 ↑
Glutactina FBgn0001114 6 5 0.83 0.6495 ↓
Walrusa FBgn0010516 7 7 1 1 ↓
CG2604a FBgn0037298 1 1 1 1 ↓
RFABGa FBgn0016724 114 115 1.01 0.9141 ↓
yip2a FBgn0040064 10 16 1.6 0.0765 ↓
CG15828a FBgn0032136 0 1 NA 0.4226 ↓
CG14688a FBgn0037819 0 1 NA 0.4226 ↓
Fat body protein 1b FBgn0000639 25 0 0.00 * 0.0202* NC
Larval serum protein 2b FBgn0002565 37 2 0.05* 0.0024* NC
Troponin C at 73Fb FBgn0010424 18 1 0.06* 0.0034* NC
PHGPxb FBgn0035438 12 1 0.08* 0.0082* NC
Diphenol oxidase A2b FBgn0000486 12 2 0.17* 0.0132* NC
Rpt1b FBgn0028687 13 3 0.23* 0.0419* NC
Muscle-specific protein 300b FBgn0053715 23 6 0.26* 0.0273* NC
Ribosomal protein S17b FBgn0005533 14 4 0.29* 0.0217* NC
Tropomyosin 2b FBgn0004117 23 7 0.30* 0.0499* NC
CG11089b FBgn0039241 15 5 0.31* 0.0099* NC
cheeriob FBgn0014141 28 10 0.36* 0.0043* NC
stab FBgn0003517 17 7 0.41* 0.0133* NC
sallimusb FBgn0003432 64 26 0.41* 0.0102* NC
bentb FBgn0005666 156 66 0.42* 0.0022* NC
regucalcinb FBgn0030362 30 14 0.47* 0.0241* NC
CG14961b FBgn0035439 17 8 0.47* 0.0031* NC
Tropomyosin 1b FBgn0003721 51 25 0.49* 0.0188* NC
Ribosomal protein S3Ab FBgn0017545 18 9 0.5* 0.0351* NC
CG3523b FBgn0027571 26 56 2.15* 0.0013* NC
TER94b FBgn0024923 18 40 2.22* 0.0012* NC
CG3731b FBgn0038271 9 26 2.89* 0.0027* NC
Elongation factor 1 βb FBgn0028737 4 13 3.25* 0.0286* NC
Ferritin 1 heavy chain homologueb FBgn0015222 3 12 4.00* 0.0350* NC
Ras oppositeb FBgn0004574 3 15 5.00* 0.0080* NC
comatoseb FBgn0000346 3 22 7.33* 0.0019* NC
stoned Ab FBgn0016976 2 15 7.50* 0.0059* NC
Trehalose-6-phosphate synthase 1b FBgn0027560 1 13 13.00* 0.0011* NC
a

Gene name or ID was obtained from reference 22.

b

Gene name or ID was obtained from reference 17.

c

The number of peptide hits (PH) is the total number of PH from the triplicate analyses.

d

The PH ratio is relative to the control. The * indicates that the protein meets our criteria (described in the experimental section) and is considered to be significantly changed.

e

P-value was obtained from Student’s t-test (two-tailed distribution and two sample unequal variance) of PH from triplicate analyses in Microsoft Excel.

f

mRNA information was obtained from reference 22. The symbols ↓, ↑ and NC indicate that the mRNA abundance was down regulated, up regulated and not changed in A30P α-synuclein transgenic flies compared to age-matched controls, respectively.