Figure 8.
Spike synchrony in a KI mouse model of HD. A, B, Sharp peaks often occur in cross-correlation histograms constructed from WT neuronal pairs (A), but not KI (B). C, D, Examples of enlarged cross-correlation histograms from WT and KI mice with expected means and 99% confidence limit. E, F, Spike trains from WT mice contained a large number of synchronous spikes (E), which were noticeably absent from KI mice (F). Calibration: 250 ms. Sig refers to a signal recorded from a single unit.