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. Author manuscript; available in PMC: 2008 Dec 8.
Published in final edited form as: Nucl Med Biol. 2008 Aug;35(Suppl 1):S27–S34. doi: 10.1016/j.nucmedbio.2008.04.007

Table 1.

An overview clinical characteristics of pheochromocytomas/paragangliomas and carcinoids

Pheochromocytomas/paragangliomas Carcinoids
Epidemiology 1–4/106 1–2/106
Localization Adrenal and extra-adrenal (mainly torso) Fore-, mid- and hindgut
Genetics Mostly sporadic; however an increasing number of patients (>20%) are currently found to have mutations in RET, VHL, NF-1, SDHx Mostly sporadic; mutations in MEN1, bcl2
Products Catecholamines Serotonin
Signs Tachycardia, diaphoresis, hypertension (paroxysmal); pallor Excess gastrointestinal motility
Symptoms Cephalalgia, Palpitations Flushing
Anatomical imaging CT, MRI CT, MRI
Functional imaging [18F]DA, [18F]DOPA, [123I]MIBG, SRS [18F]DOPA, [11C]5-HTP, SRS
Median survival 50% 67%

Please see text for abbreviations