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. Author manuscript; available in PMC: 2009 Nov 12.
Published in final edited form as: FEBS Lett. 2008 Oct 21;582(27):3823–3831. doi: 10.1016/j.febslet.2008.10.015

Fig. 3.

Fig. 3

The activation of Src-kinase, MEK1/2, ERK1/2 and p38 MAP kinases in astroglial cells from the PPT1 KO mice. (A) Western blot analyses of WT and PPT1-KO astroglial cell extracts using anti-phospho-Src antibody; anti-c-Src was used as the control. (B) Western blot analyses of WT and PPT1-KO astroglial cell extracts using anti-phospho-MEK1/2 antibody; anti-MEK1/2 was used as the control. (C) Western blot analyses of WT and PPT1-KO astroglial cell extracts using anti-phospho-ERK1/2 antibody; anti- ERK1/2 was used as the control. (D) Western blot analyses of WT and PPT1-KO astroglial cell extracts using anti-phospho-p38 antibody; anti- p38 was used as the control. Note the elevation of Src- and MAPK- phosphorylation in PPT1-KO astroglial cells. The error bars indicate standard deviation of the mean (n=3).