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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Steroids. 2008 May 18;73(11):1160–1173. doi: 10.1016/j.steroids.2008.05.003

Figure 3. Multiple sequence alignment of human Class II PAQRs.

Figure 3

This alignment was originally performed using ClustalX but was modified manually afterwards. TM and loop regions (L) are numbered. Predicted TMs are also boxed. Black shading shows amino acids that are highly, but not universally, conserved in the entire PAQR family. Grey shading indicates amino acids that are conserved in all vertebrate members of the mPRγ/PAQR6 clade, although only human sequences are shown. Circled amino acids indicate the positions of intron/exon boundaries in the pre-mRNA. Arrow indicates the location of truncations in the mPRγ and mPRα proteins discussed in Figure 7.