Table 5.

Multivariable modeling results for base excess

Multivariable Model of Base Excess†
Predictor		Estimate (95% CI)	P Value
Time (min)	0	Reference
	15	−14.3  (−16.3, −12.3)	< 0.0001‡
	30	−14.4  (−16.6, −12.2)	< 0.0001‡
	60	−12.4  (−14.7, −10.1)	< 0.0001‡
	90	−9.4  (−11.6, −7.1)	< 0.0001‡
	120	−7.7  (−10.0, −5.5)	< 0.0001‡
	180	−4.6  (−7.0, −2.3)	0.0008‡
Gender	Male	Reference
	Female	−2.2  (−3.6, −0.8)	0.0016
VF Type	Electrical	Reference
	Ischemic	−4.8  (−6.2, −3.4)	< 0.0001

^†Estimates in mEq/L of base excess, relative to a reference measurement of base excess in a male animal, undergoing electrical VF induction, at time zero.

^‡P Values corrected for multiple comparisons to baseline at time zero, using the Dunnett-Hsu correction.