Table 3.
Thermodynamic parameters from van’t Hoff analysis of the thermal denaturation of sequences forming unimolecular antiparallel quadruplexes in 25 mM KCl
Sequence | Tm (°C, ± 0.5) | ΔH° (kcal/mol, ±2) | ΔS° (cal/(mol-deg), ±4) | ΔG°(37 °C) (kcal/mol, ±0.2) |
---|---|---|---|---|
dTBA | 45.9 | 40.3 | 127 | 0.93 |
dTBAr2 | 51.8 | 45.3 | 139 | 2.21 |
rTBAd1 | 49.4 | 46.2 | 144 | 1.72 |