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Linear maps of the complete heavy (A) and light (B) chain DNA constructs used to generate anti-alpha3(IV)NC1 collagen H+L Ig transgenic mice. Solid boxes depict exons; EcoRI, R; XhoI, X; Not1, N; Sal1, S. The restriction fragments containing the rearranged VDJ or Vk-Jk2 genes and leader sequences also contain the Ig transcriptional control elements (Ig promoter, P; Ig heavy chain enhancer, E; kappa chain enhancer, Ek).
