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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: J Immunol. 2008 Nov 1;181(9):6092–6100. doi: 10.4049/jimmunol.181.9.6092

Figure 6.

Figure 6

Transgene expression in Rag-deficient anti-alpha3(IV)NC1 collagen H+L Ig Tg mice. A) Serum total IgM concentration in μg/ml as determined by ELISA. Median in μg/ml, 287.5 non-Tg Rag-sufficient, 0.0 non-Tg Rag-deficient, 227.6 Tg Rag-sufficient, and 0.31 Tg Rag-deficient, p<0.001. B) Number of B220+ cells in spleen as by determined by flow cytometry. Median in μg/ml, 39.2 non-Tg Rag-sufficient, 1.0 non-Tg Rag-deficient, 19.4 Tg Rag-sufficient, and 0.7 Tg Rag-deficient, p<0.001. n=4-7 mice/group.