. Author manuscript; available in PMC: 2009 Nov 1.

Published in final edited form as: J Immunol. 2008 Nov 1;181(9):6092–6100. doi: 10.4049/jimmunol.181.9.6092

Table I.

Splenic profiles of anti-alpha3(IV)NC1 collagen Ig Tg mice

	Non-Tg	Tg	p value
Spleen weight (mg)	73 (69,76)	49 (44, 58)	< 0.01
Spleen cells (millions)^*	83.8 (68.5, 98)	38 (27.4, 43.1)	< 0.0001
%B220+	56.8 (54.5, 58.4)	32.5 (31.2, 34.4)	< 0.0001
B cells (millions)	37 (32.3, 42.3)	9.4 (6.9, 12)	< 0.0001
%CD3+	35.7 (31.8, 36.1)	55.7 (53.5, 56.7)	< 0.0001
T cells (millions)	27.1 (20.9, 28.2)	17.5 (13.2, 18.7)	< 0.01

Splenocyte suspensions from Tg and non-Tg littermates were depleted of erythrocytes and enumerated, and B220 and CD3 subpopulations were identified using flow cytometry. Percentages of positive cells are derived from dot plots after gating on small lymphocytes using side and forward scatter. Values are median (25^th, 75^th percentile); n=9-11 mice/group.