Table 1. Time to appearance of anti-HCV antibodies, ALT elevation and HCV RNA detection.
| Marker | Estimates | Model in baseline analysis | Models in sensitivity analysis |
| Anti-HCV antibodies | m = 66 days (SD = 28);24 82 days (range, 54–192)25 | Normal distribution (m = 66; SD = 28) | Normal distribution (m = 49; SD = 21) or Normal distribution (m = 82; SD = 28) |
| ALT | Median at 46 days;27 1–2 weeks before HCV seroconversion28 | Exponential distribution (λ* = 0.015) | Exponential distribution (λ = 1/52) or Exponential distribution (λ = 1/59) |
| HCV RNA | m = 10 days;24 1–2 weeks29 | Normal distribution (m = 10; SD = 3.5) | Normal distribution (m = 7; SD = 3.5) or Normal distribution (m = 14; SD = 7) |
*λ is the parameter of the exponential distribution which is equal to ln(2) divided by the median time of elevation of ALT, which was set at 46 days in the base case analysis.27
ALT, alanine transaminase; HCV, hepatitis C virus; m, mean.