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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Pharmacol Biochem Behav. 2008 Jul 25;91(2):217–222. doi: 10.1016/j.pbb.2008.07.014

Fig 3.

Fig 3

Effect of α1AR blockade on modafinil-induced locomotion. Dbh +/− and Dbh −/− mice were placed in locomotor activity chambers and injected with vehicle or prazosin (0.5 mg/kg, i.p.) 3.5 hours later. Thirty minutes following the pretreatment, mice were injected with modafinil (50 mg/kg, i.p.), and ambulations (consecutive beam breaks) were recorded for an additional 2 hours. Shown are the total ambulations for the 2 hours after modafinil administration. * P < 0.05 compared to vehicle control for that genotype.