Table 3. Genotyping Statistics for TAS1R SNPs tested in the AFDS.

Chromosome, Position (kb)	SNP ID	Linked Gene	Call Rate (%)	HWE P Value	Major / Minor Allele	MAF§	SNP Type	T2DM Association P Value
1, 6546	RS4908563	TAS1R1	98.9	0.014	T/C	0.46	intronic	0.65
1, 6562	RS4908932	TAS1R1	93.5	0.194	G/T	0.17	noncoding	0.54
1, 19037	RS12036097	TAS1R2	97.2	0.112	G/A	0.46	noncoding	0.62
1, 19037	RS12034674B	TAS1R2	85.9	0.669	C/T	0.29	noncoding	N/A
1, 19040	RS3935570	TAS1R2	96.0	0.227	G/T	0.17	intronic	0.77
1, 19042	RS12137730A	TAS1R2	90.8	0.085	A/C	0.46	intronic	N/A
1, 19043	RS12567264	TAS1R2	93.2	0.132	T/A	0.29	Intronic	0.95
1, 19043	RS7534618	TAS1R2	97.6	0.148	T/G	0.29	intronic	0.86
1, 19044	RS12408808	TAS1R2	97.4	0.526	G/A	0.24	intronic	0.44
1, 19050	RS4076838	TAS1R2	93.8	0.525	T/C	0.29	intronic	0.30
1, 19052	RS4920564	TAS1R2	95.7	0.191	T/G	0.42	intronic	0.11
1, 19052	RS4920566	TAS1R2	96.6	0.378	A/G	0.25	intronic	0.97
1, 19054	RS28470550	TAS1R2	93.6	0.109	A/C	0.39	T294T	0.87
1, 19059	RS9701796	TAS1R2	96.9	0.866	G/C	0.11	C9S	0.29

TAS1R SNPs found to be monomorphic in the AFDS: rs6662276, rs12030791, rs12030797, rs307377, rs10864628, and rs28374389 (All TAS1R3 SNPs were monomorphic).

^Aexcluded from further analysis due to genotype quality control issues.

^BExcluded from further analysis due to call rate <90%.

kb, kilobases.

MAF, minor allele frequency.

Covariates: age, sex, BMI, and with adjustments for family structure.