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. 2008 Dec 18;3(12):e3968. doi: 10.1371/journal.pone.0003968

Table 3. Alternative RNA splicing in α-MHC-LacZ-(CTG)400 hearts.

Gene Accession no. Alt. spliced exon number n % Exons inclusion
WT adult LacZ adult TGhigh adult Tglow adult WT Posnatal day 1 WT Posnatal day 2
Tnnt2 NM_011619 5 3 6.8±1.15 6.15±1.1 6.9±1.3 7.5±0.9 24.3±1.7* 22.2±1.6*
Alp AF002283 5a 3 81.7±2.0 80.2±1.6 80.5±1.8 81.1±2.5 98.2±0.5* 97.7±1.0*
Zasp AY206013 11 3 67.9±4.7 65.5±3.1 67.6±4.1 69.1±5.3 91.6±0.7* 89.7±1.3*
m-Ttn XM_130312 Mex5 3 48.7±1.2 47.6±1.3 48.2±1.3 47.4±0.9 98.6±0.4* 98.4±0.5*

Asterisk (*) represents significant differences from wild type (WT) adult (Student's t-test; p<0.05). Tnnt2, cardiac troponin T; Alp, alpha-actinine-2 associated LIM protein; Zasp, Z-band alternatively spliced PDZ-motif protein; m-Ttn, M-line Titin; LacZ, α-MHC-LacZ-(CTG)0; TGhigh, α-MHC-LacZ-(CTG)400TGhigh; TGlow, α-MHC-LacZ-(CTG)400TGlow.