Table 4.

Genes most highly repressed upon IbsC, ShoB, LdrD and TisB overexpression^a

Gene	Descriptionb	Regulationc	Average fold repression
			IbsC	LdrD	TisB	ShoB
dusB/yhdG	tRNA dihydrouridine synthase B	CRP, IHF, Fis	6.5	0.9	1.1	4.3
fis	Transcriptional activator		7.7	0.9	1.1	3.8
yeeF	Putative transporter		17.8	0.8	1.2	4.7
apt	Adenine phosphoribosyl transferase		6.1	0.9	1.2	2.3
efeU (ycdN)	Inactive ferrous iron permease	CpxR	21.2	1.2	2.1	1.2
efeO (ycdO)	Inactive ferrous iron transporter		14.3	1.0	1.8	1.2
efeB (ycdB)	Inactive ferrous iron transporter		2.6	1.8	0.9	1.2
ompF	Porin	OmpR, EnvYd	6.1	1.4	0.9	0.5
yagU	Unknown		26.7	1.7	2.5	1.2

^aGenes and operons which are repressed ≥5-fold in three independent experiments are listed with the average fold repression for the three experiments. Boxes are shaded for those genes and operons repressed ≥ 2-fold in all experiments.

^bDescriptions of gene function are taken from EcoGene (http://ecogene.org/).

^cInformation about regulation is taken from RegulonDB (http://regulondb.ccg.unam.mx/).

^dAlso regulated by Crp, IHF, Lrp, CpxR, RstA, Fur as well as σ^E (Rhodius et al., 2006).