Fig. 6.

Segmentation method applied to data set M3 (malignant lesion, ductal carcinoma in situ) and resulting in four clusters. The left image shows the cluster distribution for each slice ranging from 6 to 8. The right image presents for each cluster the representative time–series signal (displayed as relative enhancement curves) and the corresponding quantities initial signal change (sa_i) and postinitial signal change (sv_p). The pseudo-color images indicate a lesion core of malignant tissue exposing signals with a strong uptake but weak wash-out. Voxels at the lesion margin expose persistently enhancing time–signal intensity curves.