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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Oct 21;876(1):69–75. doi: 10.1016/j.jchromb.2008.10.022

Figure 2.

Figure 2

Typical chromatograms obtained on an HSA column during (a) frontal analysis experiments with S-verapamil and (b) competitive experiments performed by zonal elution in which S-warfarin was the injected analyte and racemic verapamil was used as a mobile phase additive. The concentrations that are shown represent the concentration of (a) S-verapamil or (b) racemic verapamil that was applied in to the HSA column. These studies were conducted at 37°C in the presence of pH 7.4, 0.067 M phosphate buffer. Other experimental conditions are given in Section 3.3.