Skip to main content
. 2006 Sep 13;44(1):44–50. doi: 10.1136/jmg.2006.045153

Table 4 Allele frequencies for polymorphisms in TCERG1 and GRIN2A.

Gene Allele number or genotype Presumed (Gln‐Ala)n repeat number Population allele frequency (%) Mean age of onset
TCERG1 289 35 2.5 29.3
294 36 0.8 41.4
300 37 0.2 38.5
306 38 95.4 34.8
318 40 0.7 26.3
328 41.5 0.3
GRIN2A C/C 4.7 33.8
C/T 39.5 32.3
T/T 55.8 36.2

TCERG1 genotypes were determined for 728 people (410 of whom are affected with Huntington's disease). No affected people had a TCERG1 328 allele. Repeat length was inferred on the basis of the length of the amplified PCR products and the published sequence. GRIN2A genotypes were determined for 731 people (405 of whom were affected with Huntington's disease). Allele frequencies are calculated from all people. Mean age of onset is calculated from affected people.