Figure 1 Pedigree and photographs of members of a family with partial lipodystrophy. (A) Pedigree of the family. The index patient is marked with an arrow. Filled symbols, affected members; unfilled symbols, unaffected patients; symbol with a diagonal line, deceased member. (B) Index patient (II.1), showing loss of fat and muscular hypertrophy especially of the legs, and accumulation of subcutaneous fat on the trunk and in the face. (C) The index patient's mother (I.1) shows similar clinical features. Parental/guardian informed consent was obtained for publication of this figure.