Table 1 Genome‐wide scans for coronary artery disease and myocardial infarction.
Reference | Study population | Families | Age (years) | Primary locus | Analysis program | Gene | |
---|---|---|---|---|---|---|---|
Pajukanta4 | Finnish | 156 | <55 | 2q21 | MAPMAKER | ND | |
Francke5 | Mauritian | 99 | 47 | 16p13 | GENEHUNTER | ND | |
Broeckel6 | European | 513 | 52 | 14 | SOLAR | ND | |
Harrap7 | Australian | 61 | 62 | 2q36 | MAPMAKER | ND | |
Wang8 | American | 428 | 44 | 1p34 | SAGE | ND | |
Hauser9 | Euro‐Amer | 438 | 56 | 3q13 | GENEHUNTER | ND | |
Helgadottir10 | Icelandic | 296 | — | 13q12 | ALLEGRO | ALOX5AP | |
Helgadottir11 | Icelandic | 296 | — | 12q22 | ALLEGRO | LTA4H | |
Brit Ht Found12 | British | 1933 | 53 | 2p11 | ALLEGRO | ND |
Brit Ht Found, British Heart Foundation; Euro‐Amer, European‐American; ND, not determined. Modified from Topol et al.2