Figure 2 Boundary sequences of the deleted fragments. The boundary sequences of four different types of GLDC deletions were identified: the deletion of exon 9 in family B7 (A), the deletion of exons 5–8 in family B18 (B), the deletion of exons 3–21 in family B6 (C) and the deletion of exons 12–15 in family P74 (D). The boundary sequence found in family P74 was the same as that in family P8. Nucleotide sequences in red indicate the identical bases in the 5′ and 3′ flanks of the deletions.